IonOptix has expanded the functionality of its IonWizard core acquisition software to include increased hardware control as well as a new software module that improves the breadth of the MyoStretcher myocyte stretch and force measurement system, an integrated, full featured system that enables scientists to investigate muscle mechanics at the single cell level while synchronously recording quantitative fluorescence and sarcomere length. The MyoStretcher has been engineered to attach single myocytes and detect the nanoscopic forces generated during contractile events, thanks to the development of our OptiForce, an exquisitely fast and sensitive force transducer. The next step in the evolution of this system is our Advanced Signal Generator, a full suite of programmable mechanical protocols that allow users to drive fast cell length changes when coupled to the MyoStretcher’s piezo-driven length controller, the first to bring this level of sophisticated experimentation to single cell studies. Basic signals will be available in IonWizard’s core functionality, while more complex protocols are available in our Advanced Signal Generator add-on module.
Investigations into the mechanical properties of myocytes require a system that enables scientists to perform a number of mechanical perturbations to the physical length of the myocyte while simultaneously recording other important parameters (calcium and sarcomere length, in particular). The IonOptix Advanced Signal Generator is the ideal tool for programmed length control.
Note: This product is intended for research purposes only. It is not certified for clinical applications (including diagnostic purposes). Use of this product in uncertified applications is in violation of FDA regulations.