Overview Fluorescence signal quality is directly proportional to fluorescence light intensity (which is proportional to excitation light intensity, fluorescence yield of the fluorophore, and light …

Engineered skeletal muscle from electrically stimulated myoblast cells Check out this video from researchers at the Department of Biomedical Engineering, Eindhoven University of Technology.

Check out this video from researchers at the Department of Internal Medicine B, University Medicine Greifswald.

Interest in the physiology and pathology of the circulatory system has led to a substantial increase in the number of laboratories studying isolated and pressurized blood vessels.

Raake, P. W., Vinge, L. E., Gao, E., Boucher, M., Rengo, G., Chen, X., DeGeorge Jr., B.R., Matkovich, S., Houser, S.R., Most, P., Eckhart, A.D., Dornll, G.W., and Koch, W. J. (2008). Circulation Research, 103(4), 413-422

Kroll, K., Chabria, M., Wang, K., Häusermann, F., Schuler, F., & Polonchuk, L. (2017). Progress in Biophysics and Molecular Biology, 130, 212-222

New technology now provides investigators the ability to reliably attach myocytes, mechanically stretch them, make direct force measurements and control cell length intelligently. This webinar reviews best-practices and techniques for attaching, stretching, and studying isolated cells.

A special webinar for basic cardiovascular researchers interested in a novel technique for measuring work output and replicating the four phases of the cardiac cycle at the single cell level.

Ronglih Liao and Davor Pavlovic discuss techniques for isolating myocytes using both traditional and Langendorff-free methodologies.

Misior, A. M., Deshpande, D. A., Loza, M. J., Pascual, R. M., Hipp, J. D., & Penn, R. B. (2009). American Journal of Respiratory Cell and Molecular Biology, 41(1), 24-39

Michiel Helmes, PhD presents new technology and methodology for fast data acquisition and functional analysis of cardiac myocytes, leading to better lab practices and data interpretation.

Orfanos, Z., Gödderz, M. P., Soroka, E., Gödderz, T., Rumyantseva, A., van der Ven, P.F.M, Hawke, T.J., Fürst, D. O. (2016). Scientific Reports, 6(1)

Myocyte contractile activity modulates norepinephrine cytotoxicity and survival effects of neuregulin-1beta. Kuramochi Y1, Lim CC, Guo X, Colucci WS, Liao R, Sawyer DB Abstract: The [...]

The transcription factor NFAT (nuclear factor of activated T-cells) is implicated in cardiac hypertrophy and vasculogenesis. NFAT activation, reflecting dephosphorylation by the calcium-dependent phosphatase, calcineurin, [...]

Rapid electrical stimulation induces early activation of kinase signal transduction pathways and apoptosis in adult rat ventricular myocytes. Kuramochi Y1, Guo X, Sawyer DB, Lim [...]

Induction of heat shock response protects the heart against atrial fibrillation. Brundel BJ, Shiroshita-Takeshita A, Qi X, Yeh YH, Chartier D, van Gelder IC, Henning [...]

Myogenic behavior, prevalent in resistance arteries and arterioles, involves arterial constriction in response to intravascular pressure. This process is often studied in vitro by using [...]

Overexpression of Na+/Ca2+ exchanger alters contractility and SR Ca2+ content in adult rat myocytes. Zhang XQ, Song J, Rothblum LI, Lun M, Wang X, Ding [...]

The control of Ca2+ influx and NFATc3 signaling in arterial smooth muscle during hypertension. Nieves-Cintrón M, Amberg GC, Navedo MF, Molkentin JD, Santana LF Abstract: [...]